Omega 3 Essential Fatty Acids and Their Role in Human Health | SA Wellness Centre

Omega 3 Essential Fatty Acids and Their Role in Human Health

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Omega 3 fatty acids are renowned for their ability to promote healthy ageing in addition to combating some diseases such as Alzheimer’s, cardiovascular diseases and promoting fetal development. What exactly are omega 3 fatty acids and how can we get more of it in our diet?

Despite having a significant impact on human health, Omega 3 fatty acids are not naturally produced in the human body. Due to this reason, we must depend on external sources of omega 3 to obtain the necessary amounts, typically from fish and fish oil.

There are two main types of omega 3 fatty acids referred to as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). According to numerous studies, EPA and DHA are essential for the correct development of a fetus, playing a major role in neuronal, retinal and immune system functionality. These fatty acids are also responsible for proper cardiovascular function, significantly affecting inflammation, anticoagulation, peripheral artery disease and coronary events. Studies have also shown the role of EPA and DHA in mild Alzheimer patients in prevention and improved cognitive function1. Omega 3 fatty acids also play a role in weight management.

Fish is a good source of Omega 3.

Oily fish, such as salmon, is a good source of omega 3 fatty acids.

According to studies that have been conducted on the basis of large populations, it has been identified that consumption of boiled or baked fish is associated with a reduction in systemic vascular resistance and reduced heart rate.

These studies also show a correlation between the consumption of fish and reduced risk of ischemic heart disease and heart failure2, 3, 4. Consuming fish in one or two servings per week has been identified to lower the risks of coronary death and total mortality5.

In fact, it is recommended by the Dietary guidelines of Australia, United Kingdom, United States and many other countries to include a variety of fish in your meals at least twice every week. This includes oily fish such as salmon, mackerel and herring as these types of fish are known for their high amounts of EPA and DHA. The inclusion of fish is observed in the Mediterranean diets more than in Western diets.

The Mediterranean diet includes nuts, cereal, vegetables, olive oil and poultry but does not include a lot of red meat and processed dairy products. Studies show that the Mediterranean diet, which encompasses fish as a major component in it, to be associated with reduced risk of cardiovascular diseases6.

A recent randomised trial of more than 7000 people showed that a Mediterranean diet rich in extra virgin olive oil or nuts could significantly decrease the events associated with cardiovascular diseases such as myocardial infarction and stroke. However, when it comes to the Western diet, the major foods include red meats and a reduced consumption of fish, nuts and other foods rich in omega 3 fatty acids is observed.

More than 3/4 of the Australian population does not meet the recommended intake of omega 3 acids.

Recent statistics show that the Western world is dangerously deficient in omega 3 fatty acids. According to National Nutrition and Physical Activity Survey, it can be seen that a slight increase in the omega 3 fatty acid intake and a reduction in the intake of polyunsaturated fats is observed since 1995, which is good. However, despite the slight increase, more than three quarters of the Australian population does not meet the recommended intake of omega 3 acids. It was also observed that 90% of pregnant mothers also do not meet the recommended levels of omega 3s during pregnancy and lactation7.

Human evolution saw a diet consisting of balanced omega 3s and omega 6 fatty acids for thousands of years. Various human and animal studies have identified that an increase in the omega 6 fatty acids over the omega 3s is associated with weight gain. These studies also show that increased omega 3 fatty acids are associated with decreased risks of overweight and obesity. Thus, it is important to maintain a good balance between omega 3 and 6 fatty acids.

Eggs, walnuts, pumpkin seeds and canola oil are great sources of omega 3 fatty acids.

Eggs, walnuts, pumpkin seeds and canola oil are great sources of omega 3 fatty acids.

It is important to identify which foods are rich in omega 3 fatty acids as well as those rich in omega 6. Omega 3 fatty acids contain EPA and DHA, which is abundant in oily fish. There is also another component of omega 3 fatty acids, which is known as ALA (alpha-linolenic acid). ALA is found in plant products.

Canola oil contains the highest amount of omega 3 fatty acids from all other cooking oils, in the form of ALA. A single tablespoon of canola oil contains around 1300mg of ALA. The Institute of Medicine recommends a minimum of 1100mg of ALA per day for men and 1600mg or more per day for women.

In addition to canola oil, flaxseed oil, flaxseed, wild rice, eggs, soybeans and nuts such as walnuts contain omega 3 fatty acids. A number of sources contain omega 6 fatty acids such as hempseed, grape seed, flaxseed and their associated oils, pumpkin and raw sunflower seeds, pistachios and pignolia nuts as well as borage oil, evening primrose oil and blackcurrant seed oil.

The modern Western diet is very high in omega 6 polyunsaturated fatty acids and have high omega 6/omega 3 ratio, which is identified to cause a huge number of diseases. Increasing the intake of omega 3 fatty acids can have a suppressing effect on such diseases8.

Omega 3 deficiencies can cause various problems.

Omega 3 deficiencies can cause various problems.

Deficiencies in omega 3 fatty acids can cause a number of symptoms. These problems include dry skin, rough skin, brittle nails, allergies such as eczema, dry eyes and dandruff.

Omega 3 deficiencies have also been identified to cause attention and concentration problems in addition to mood related problems such as anxiety, irritability and depression. Signs and symptoms of fatigue and poor sleep can also be observed in addition to joint pain and other inflammation related signs.

There is a large market for omega 3 fatty acids as their importance is identified all over the world. However, it is important to obtain these fatty acids in their natural form. Omega 3 fatty acids naturally occur in the form of triglycerides. If the omega 3 you obtain is produced in this form, they will be more stable and will be absorbed easily by the body.

Ethyl esters is another form of omega 3s that are easy and cheaper to produce. These are also known as fish oil concentrates. However, this form is somewhat difficult for the body to digest and absorb in contrast to the triglyceride form. Therefore it is better to obtain omega 3 fatty acids in their natural form.

Meeting the recommended intakes for n-3 LCPUFA with and without supplements

Recommended Intakes for Females
19+ Years
Females 19+ Years
(n = 5059)
No Supplements
(n – 4054, 75%)
With Supplements
(n = 1005, 25%)
>430 mg per day * n = 1126 (22%) n = 446 (11%) n = 673 (67%)
>500 mg per day # n = 1001 (20%) n = 386 (9.5%) n = 613 (61%)
Recommended Intakes for Males
19+ Years
Males 19+ Years
(n = 4282)
No Supplements
(n – 3625, 85%)
With Supplements
(n = 657, 15%)
>500 mg per day * n = 844 (20%) n = 399 (11%) n = 368 (56%)
>610 mg per day # n = 702 (16%) n = 326 (9%) n = 302 (46%)

* National Health & Medical Research Council (NHMRC) nutrient reference values (NRV) suggested dietary target (SDT) intakes for adult females and males.

# ISSFAL recommendations for cardiovascular health.

n-3 LCPUFA = omega-3 long chain polyunsaturated fatty acids, n = number of participants
Less than a quarter of Australian adults are meeting the n-3 LCPUFA recommendations for optimal health. However, those adults consuming n-3 LCPUFA supplements approximately 50% are meeting the recommended intakes, whilst those not consuming supplements, only approximately 10% are meeting the recommended intakes.

References

  • Danielle Swanson, Robert Block, Shaker A. Mousa; Omega-3 Fatty Acids EPA and DHA: Health Benefits Throughout Life, Advances in Nutrition, Volume 3, Issue 1, 1 January 2012, Pages 1–7, https://doi.org/10.3945/an.111.000893
  • Mozaffarian D, Bryson CL, Lemaitre RN, Burke GL, Siscovick DS. Fish intake and risk of incident heart failure. J Am Coll Cardiol. 2005;45(12):2015–21. [PubMed]
  • Mozaffarian D, Gottdiener JS, Siscovick DS. Intake of tuna or other broiled or baked fish versus fried fish and cardiac structure, function, and hemodynamics. Am J Cardiol. 2006;97(2):216–22. [PubMed]
  • Mozaffarian D, Prineas RJ, Stein PK, Siscovick DS. Dietary fish and n-3 fatty acid intake and cardiac electrocardiographic parameters in humans. J Am Coll Cardiol. 2006;48(3):478–84. [PubMed]
  • Mozaffarian D, Rimm EB. Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA. 2006;296(15):1885–99. [PubMed]
  • Estruch R, Ros E, Salas-Salvadó J, Covas MI, Corella D, Arós F, et al. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013;368(14):1279–90. [PubMed]
  • Meyer, B. J. (2016). Australians are not Meeting the Recommended Intakes for Omega-3 Long Chain Polyunsaturated Fatty Acids: Results of an Analysis from the 2011–2012 National Nutrition and Physical Activity Survey. Nutrients, 8(3), 111. http://doi.org/10.3390/nu8030111
  • AP, Simopolous. (2018). The importance of the ratio of omega-6/omega-3 essential fatty acids. – PubMed – NCBI. [online] Ncbi.nlm.nih.gov. Available at: https://www.ncbi.nlm.nih.gov/pubmed/12442909 [Accessed 30 Mar. 2018].
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